Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication
Identifieur interne : 000128 ( an2020/Analysis ); précédent : 000127; suivant : 000129Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication
Auteurs : Yuka Horio [Japon] ; Riho Sogabe [Japon] ; Mototada Shichiri [Japon] ; Noriko Ishida [Japon] ; Ryosuke Morimoto [Japon] ; Atsushi Ohshima [Japon] ; Yuji Isegawa [Japon]Source :
- Journal of Clinical Biochemistry and Nutrition [ 0912-0009 ] ; 2020.
Abstract
This study was conducted to evaluate the regulation mechanism of influenza virus replication following treatment of Madin-Darby canine kidney cells with the soy isoflavone daidzein. We performed comparative qualitative and quantitative analyses of lipid peroxide between mock-infected and virus-infected cells treated with or without daidzein, as it had been reported that daidzein was an antioxidant and lipid peroxide levels increased upon virus infection. Contrary to our belief, lipid peroxides were not elevated in virus-infected cells and no decrease in lipid peroxides was observed in daidzein-treated cells. In daidzein-treated cells, 5-hydroxyeicosatetraenoic acid, the 5-lipoxygenase product derived from arachidonate, was significantly elevated compared to other lipid peroxides. Zileuton (5-lipoxygenase inhibitor) and 5-lipoxygenase knockdown reduced the daidzein-induced antiviral effect. Moreover, virus replication was regulated by treatment with 5-hydroperoxyeicosatetraenoic acid, a precursor of 5-hydroxyeicosatetraenoic acid and 5-lipoxygenase primary product. These results suggest that daidzein regulates virus replication via signal transduction through 5-lipoxygenase products.
Url:
DOI: 10.3164/jcbn.19-70
PubMed: 32001954
PubMed Central: 6983437
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000662
- to stream Pmc, to step Curation: 000662
- to stream Pmc, to step Checkpoint: 000121
- to stream Ncbi, to step Merge: 000E78
- to stream Ncbi, to step Curation: 000E78
- to stream Ncbi, to step Checkpoint: 000E78
- to stream Main, to step Merge: 000128
- to stream Main, to step Curation: 000128
- to stream Main, to step Exploration: 000128
- to stream an2020, to step Extraction: 000128
Links to Exploration step
PMC:6983437Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication</title><author><name sortKey="Horio, Yuka" sort="Horio, Yuka" uniqKey="Horio Y" first="Yuka" last="Horio">Yuka Horio</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Sogabe, Riho" sort="Sogabe, Riho" uniqKey="Sogabe R" first="Riho" last="Sogabe">Riho Sogabe</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Shichiri, Mototada" sort="Shichiri, Mototada" uniqKey="Shichiri M" first="Mototada" last="Shichiri">Mototada Shichiri</name><affiliation wicri:level="1"><nlm:aff id="aff2">Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577</wicri:regionArea><wicri:noRegion>Osaka 563-8577</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), 1-1-1 Higashi, Tsukuba-shi, Ibaraki 305-8562, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), 1-1-1 Higashi, Tsukuba-shi, Ibaraki 305-8562</wicri:regionArea><wicri:noRegion>Ibaraki 305-8562</wicri:noRegion></affiliation></author><author><name sortKey="Ishida, Noriko" sort="Ishida, Noriko" uniqKey="Ishida N" first="Noriko" last="Ishida">Noriko Ishida</name><affiliation wicri:level="1"><nlm:aff id="aff2">Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577</wicri:regionArea><wicri:noRegion>Osaka 563-8577</wicri:noRegion></affiliation></author><author><name sortKey="Morimoto, Ryosuke" sort="Morimoto, Ryosuke" uniqKey="Morimoto R" first="Ryosuke" last="Morimoto">Ryosuke Morimoto</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Ohshima, Atsushi" sort="Ohshima, Atsushi" uniqKey="Ohshima A" first="Atsushi" last="Ohshima">Atsushi Ohshima</name><affiliation wicri:level="1"><nlm:aff id="aff4">Genomics Program, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-Cho, Nagahama, Shiga 526-0829, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Genomics Program, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-Cho, Nagahama, Shiga 526-0829</wicri:regionArea><wicri:noRegion>Shiga 526-0829</wicri:noRegion></affiliation></author><author><name sortKey="Isegawa, Yuji" sort="Isegawa, Yuji" uniqKey="Isegawa Y" first="Yuji" last="Isegawa">Yuji Isegawa</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5">Institute for Biosciences, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Institute for Biosciences, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32001954</idno><idno type="pmc">6983437</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983437</idno><idno type="RBID">PMC:6983437</idno><idno type="doi">10.3164/jcbn.19-70</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000662</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000662</idno><idno type="wicri:Area/Pmc/Curation">000662</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000662</idno><idno type="wicri:Area/Pmc/Checkpoint">000121</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000121</idno><idno type="wicri:Area/Ncbi/Merge">000E78</idno><idno type="wicri:Area/Ncbi/Curation">000E78</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E78</idno><idno type="wicri:doubleKey">0912-0009:2020:Horio Y:induction:of:a</idno><idno type="wicri:Area/Main/Merge">000128</idno><idno type="wicri:Area/Main/Curation">000128</idno><idno type="wicri:Area/Main/Exploration">000128</idno><idno type="wicri:Area/an2020/Extraction">000128</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication</title><author><name sortKey="Horio, Yuka" sort="Horio, Yuka" uniqKey="Horio Y" first="Yuka" last="Horio">Yuka Horio</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Sogabe, Riho" sort="Sogabe, Riho" uniqKey="Sogabe R" first="Riho" last="Sogabe">Riho Sogabe</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Shichiri, Mototada" sort="Shichiri, Mototada" uniqKey="Shichiri M" first="Mototada" last="Shichiri">Mototada Shichiri</name><affiliation wicri:level="1"><nlm:aff id="aff2">Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577</wicri:regionArea><wicri:noRegion>Osaka 563-8577</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), 1-1-1 Higashi, Tsukuba-shi, Ibaraki 305-8562, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), 1-1-1 Higashi, Tsukuba-shi, Ibaraki 305-8562</wicri:regionArea><wicri:noRegion>Ibaraki 305-8562</wicri:noRegion></affiliation></author><author><name sortKey="Ishida, Noriko" sort="Ishida, Noriko" uniqKey="Ishida N" first="Noriko" last="Ishida">Noriko Ishida</name><affiliation wicri:level="1"><nlm:aff id="aff2">Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577</wicri:regionArea><wicri:noRegion>Osaka 563-8577</wicri:noRegion></affiliation></author><author><name sortKey="Morimoto, Ryosuke" sort="Morimoto, Ryosuke" uniqKey="Morimoto R" first="Ryosuke" last="Morimoto">Ryosuke Morimoto</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author><author><name sortKey="Ohshima, Atsushi" sort="Ohshima, Atsushi" uniqKey="Ohshima A" first="Atsushi" last="Ohshima">Atsushi Ohshima</name><affiliation wicri:level="1"><nlm:aff id="aff4">Genomics Program, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-Cho, Nagahama, Shiga 526-0829, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Genomics Program, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-Cho, Nagahama, Shiga 526-0829</wicri:regionArea><wicri:noRegion>Shiga 526-0829</wicri:noRegion></affiliation></author><author><name sortKey="Isegawa, Yuji" sort="Isegawa, Yuji" uniqKey="Isegawa Y" first="Yuji" last="Isegawa">Yuji Isegawa</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food Sciences and Nutrition, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5">Institute for Biosciences, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Institute for Biosciences, Mukogawa Women’s University, 6-46 Ikebiraki, Nishinomiya, Hyogo 663-8558</wicri:regionArea><wicri:noRegion>Hyogo 663-8558</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Clinical Biochemistry and Nutrition</title><idno type="ISSN">0912-0009</idno><idno type="eISSN">1880-5086</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>This study was conducted to evaluate the regulation mechanism of influenza virus replication following treatment of Madin-Darby canine kidney cells with the soy isoflavone daidzein. We performed comparative qualitative and quantitative analyses of lipid peroxide between mock-infected and virus-infected cells treated with or without daidzein, as it had been reported that daidzein was an antioxidant and lipid peroxide levels increased upon virus infection. Contrary to our belief, lipid peroxides were not elevated in virus-infected cells and no decrease in lipid peroxides was observed in daidzein-treated cells. In daidzein-treated cells, 5-hydroxyeicosatetraenoic acid, the 5-lipoxygenase product derived from arachidonate, was significantly elevated compared to other lipid peroxides. Zileuton (5-lipoxygenase inhibitor) and 5-lipoxygenase knockdown reduced the daidzein-induced antiviral effect. Moreover, virus replication was regulated by treatment with 5-hydroperoxyeicosatetraenoic acid, a precursor of 5-hydroxyeicosatetraenoic acid and 5-lipoxygenase primary product. These results suggest that daidzein regulates virus replication via signal transduction through 5-lipoxygenase products.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Belser, Ja" uniqKey="Belser J">JA Belser</name></author><author><name sortKey="Maines, Tr" uniqKey="Maines T">TR Maines</name></author><author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chow, Ej" uniqKey="Chow E">EJ Chow</name></author><author><name sortKey="Doyle, Jd" uniqKey="Doyle J">JD Doyle</name></author><author><name sortKey="Uyeki, Tm" uniqKey="Uyeki T">TM Uyeki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le, Qm" uniqKey="Le Q">QM Le</name></author><author><name sortKey="Kiso, M" uniqKey="Kiso M">M Kiso</name></author><author><name sortKey="Someya, K" uniqKey="Someya K">K Someya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bloom, Jd" uniqKey="Bloom J">JD Bloom</name></author><author><name sortKey="Gong, Li" uniqKey="Gong L">LI Gong</name></author><author><name sortKey="Baltimore, D" uniqKey="Baltimore D">D Baltimore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Furuta, Y" uniqKey="Furuta Y">Y Furuta</name></author><author><name sortKey="Takahashi, K" uniqKey="Takahashi K">K Takahashi</name></author><author><name sortKey="Fukuda, Y" uniqKey="Fukuda Y">Y Fukuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kiso, M" uniqKey="Kiso M">M Kiso</name></author><author><name sortKey="Takahashi, K" uniqKey="Takahashi K">K Takahashi</name></author><author><name sortKey="Sakai Tagawa, Y" uniqKey="Sakai Tagawa Y">Y Sakai-Tagawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagai, E" uniqKey="Nagai E">E Nagai</name></author><author><name sortKey="Iwai, M" uniqKey="Iwai M">M Iwai</name></author><author><name sortKey="Koketsu, R" uniqKey="Koketsu R">R Koketsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Christen, S" uniqKey="Christen S">S Christen</name></author><author><name sortKey="Peterhans, E" uniqKey="Peterhans E">E Peterhans</name></author><author><name sortKey="Stocker, R" uniqKey="Stocker R">R Stocker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jacoby, Db" uniqKey="Jacoby D">DB Jacoby</name></author><author><name sortKey="Choi, Am" uniqKey="Choi A">AM Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akaike, T" uniqKey="Akaike T">T Akaike</name></author><author><name sortKey="Noguchi, Y" uniqKey="Noguchi Y">Y Noguchi</name></author><author><name sortKey="Ijiri, S" uniqKey="Ijiri S">S Ijiri</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Jung, Ki" uniqKey="Jung K">KI Jung</name></author><author><name sortKey="Pyo, Cw" uniqKey="Pyo C">CW Pyo</name></author><author><name sortKey="Choi, Sy" uniqKey="Choi S">SY Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franke, Aa" uniqKey="Franke A">AA Franke</name></author><author><name sortKey="Lai, Jf" uniqKey="Lai J">JF Lai</name></author><author><name sortKey="Halm, Bm" uniqKey="Halm B">BM Halm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sankar, P" uniqKey="Sankar P">P Sankar</name></author><author><name sortKey="Zachariah, B" uniqKey="Zachariah B">B Zachariah</name></author><author><name sortKey="Vickneshwaran, V" uniqKey="Vickneshwaran V">V Vickneshwaran</name></author><author><name sortKey="Jacob, Se" uniqKey="Jacob S">SE Jacob</name></author><author><name sortKey="Sridhar, Mg" uniqKey="Sridhar M">MG Sridhar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author><author><name sortKey="Ma, X" uniqKey="Ma X">X Ma</name></author><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, M" uniqKey="Jin M">M Jin</name></author><author><name sortKey="Shen, Mh" uniqKey="Shen M">MH Shen</name></author><author><name sortKey="Jin, Mh" uniqKey="Jin M">MH Jin</name></author><author><name sortKey="Jin, Ah" uniqKey="Jin A">AH Jin</name></author><author><name sortKey="Yin, Xz" uniqKey="Yin X">XZ Yin</name></author><author><name sortKey="Quan, Js" uniqKey="Quan J">JS Quan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuiper, Gg" uniqKey="Kuiper G">GG Kuiper</name></author><author><name sortKey="Carlsson, B" uniqKey="Carlsson B">B Carlsson</name></author><author><name sortKey="Grandien, K" uniqKey="Grandien K">K Grandien</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuiper, Gg" uniqKey="Kuiper G">GG Kuiper</name></author><author><name sortKey="Lemmen, Jg" uniqKey="Lemmen J">JG Lemmen</name></author><author><name sortKey="Carlsson, B" uniqKey="Carlsson B">B Carlsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Uif Lean, A" uniqKey="Uif Lean A">A Uifälean</name></author><author><name sortKey="Schneider, S" uniqKey="Schneider S">S Schneider</name></author><author><name sortKey="Ionescu, C" uniqKey="Ionescu C">C Ionescu</name></author><author><name sortKey="Lalk, M" uniqKey="Lalk M">M Lalk</name></author><author><name sortKey="Iuga, Ca" uniqKey="Iuga C">CA Iuga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Folman, Y" uniqKey="Folman Y">Y Folman</name></author><author><name sortKey="Pope, Gs" uniqKey="Pope G">GS Pope</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yan, Gr" uniqKey="Yan G">GR Yan</name></author><author><name sortKey="Xiao, Cl" uniqKey="Xiao C">CL Xiao</name></author><author><name sortKey="He, Gw" uniqKey="He G">GW He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hafez, Hs" uniqKey="Hafez H">HS Hafez</name></author><author><name sortKey="Ghareeb, Da" uniqKey="Ghareeb D">DA Ghareeb</name></author><author><name sortKey="Saleh, Sr" uniqKey="Saleh S">SR Saleh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Ms" uniqKey="Kim M">MS Kim</name></author><author><name sortKey="Kim, B" uniqKey="Kim B">B Kim</name></author><author><name sortKey="Park, H" uniqKey="Park H">H Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoshida, Y" uniqKey="Yoshida Y">Y Yoshida</name></author><author><name sortKey="Kodai, S" uniqKey="Kodai S">S Kodai</name></author><author><name sortKey="Takemura, S" uniqKey="Takemura S">S Takemura</name></author><author><name sortKey="Minamiyama, Y" uniqKey="Minamiyama Y">Y Minamiyama</name></author><author><name sortKey="Niki, E" uniqKey="Niki E">E Niki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Umeno, A" uniqKey="Umeno A">A Umeno</name></author><author><name sortKey="Shichiri, M" uniqKey="Shichiri M">M Shichiri</name></author><author><name sortKey="Ishida, N" uniqKey="Ishida N">N Ishida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shichiri, M" uniqKey="Shichiri M">M Shichiri</name></author><author><name sortKey="Ishida, N" uniqKey="Ishida N">N Ishida</name></author><author><name sortKey="Hagihara, Y" uniqKey="Hagihara Y">Y Hagihara</name></author><author><name sortKey="Yoshida, Y" uniqKey="Yoshida Y">Y Yoshida</name></author><author><name sortKey="Kume, A" uniqKey="Kume A">A Kume</name></author><author><name sortKey="Suzuki, H" uniqKey="Suzuki H">H Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lisovyy, Oo" uniqKey="Lisovyy O">OO Lisovyy</name></author><author><name sortKey="Dosenko, Ve" uniqKey="Dosenko V">VE Dosenko</name></author><author><name sortKey="Nagibin, Vs" uniqKey="Nagibin V">VS Nagibin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shichiri, M" uniqKey="Shichiri M">M Shichiri</name></author><author><name sortKey="Kono, N" uniqKey="Kono N">N Kono</name></author><author><name sortKey="Shimanaka, Y" uniqKey="Shimanaka Y">Y Shimanaka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steinhilber, D" uniqKey="Steinhilber D">D Steinhilber</name></author><author><name sortKey="Fischer, As" uniqKey="Fischer A">AS Fischer</name></author><author><name sortKey="Metzner, J" uniqKey="Metzner J">J Metzner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, H" uniqKey="Liu H">H Liu</name></author><author><name sortKey="Zhong, H" uniqKey="Zhong H">H Zhong</name></author><author><name sortKey="Leng, L" uniqKey="Leng L">L Leng</name></author><author><name sortKey="Jiang, Z" uniqKey="Jiang Z">Z Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="B Ck, M" uniqKey="B Ck M">M Bäck</name></author><author><name sortKey="Yurdagul, A" uniqKey="Yurdagul A">A Yurdagul</name></author><author><name sortKey="Tabas, I" uniqKey="Tabas I">I Tabas</name></author><author><name sortKey="Oorni, K" uniqKey="Oorni K">K Öörni</name></author><author><name sortKey="Kovanen, Pt" uniqKey="Kovanen P">PT Kovanen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Serhan, Cn" uniqKey="Serhan C">CN Serhan</name></author><author><name sortKey="Dalli, J" uniqKey="Dalli J">J Dalli</name></author><author><name sortKey="Colas, Ra" uniqKey="Colas R">RA Colas</name></author><author><name sortKey="Winkler, Jw" uniqKey="Winkler J">JW Winkler</name></author><author><name sortKey="Chiang, N" uniqKey="Chiang N">N Chiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morita, M" uniqKey="Morita M">M Morita</name></author><author><name sortKey="Kuba, K" uniqKey="Kuba K">K Kuba</name></author><author><name sortKey="Ichikawa, A" uniqKey="Ichikawa A">A Ichikawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="R Dmark, O" uniqKey="R Dmark O">O Rådmark</name></author><author><name sortKey="Werz, O" uniqKey="Werz O">O Werz</name></author><author><name sortKey="Steinhilber, D" uniqKey="Steinhilber D">D Steinhilber</name></author><author><name sortKey="Samuelsson, B" uniqKey="Samuelsson B">B Samuelsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Recchiuti, A" uniqKey="Recchiuti A">A Recchiuti</name></author><author><name sortKey="Serhan, Cn" uniqKey="Serhan C">CN Serhan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="King, Ra" uniqKey="King R">RA King</name></author><author><name sortKey="Bursill, Db" uniqKey="Bursill D">DB Bursill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, Wc" uniqKey="Cheng W">WC Cheng</name></author><author><name sortKey="Lo, Sc" uniqKey="Lo S">SC Lo</name></author><author><name sortKey="Tsai, Ks" uniqKey="Tsai K">KS Tsai</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Horio, Yuka" sort="Horio, Yuka" uniqKey="Horio Y" first="Yuka" last="Horio">Yuka Horio</name></noRegion><name sortKey="Isegawa, Yuji" sort="Isegawa, Yuji" uniqKey="Isegawa Y" first="Yuji" last="Isegawa">Yuji Isegawa</name><name sortKey="Isegawa, Yuji" sort="Isegawa, Yuji" uniqKey="Isegawa Y" first="Yuji" last="Isegawa">Yuji Isegawa</name><name sortKey="Ishida, Noriko" sort="Ishida, Noriko" uniqKey="Ishida N" first="Noriko" last="Ishida">Noriko Ishida</name><name sortKey="Morimoto, Ryosuke" sort="Morimoto, Ryosuke" uniqKey="Morimoto R" first="Ryosuke" last="Morimoto">Ryosuke Morimoto</name><name sortKey="Ohshima, Atsushi" sort="Ohshima, Atsushi" uniqKey="Ohshima A" first="Atsushi" last="Ohshima">Atsushi Ohshima</name><name sortKey="Shichiri, Mototada" sort="Shichiri, Mototada" uniqKey="Shichiri M" first="Mototada" last="Shichiri">Mototada Shichiri</name><name sortKey="Shichiri, Mototada" sort="Shichiri, Mototada" uniqKey="Shichiri M" first="Mototada" last="Shichiri">Mototada Shichiri</name><name sortKey="Sogabe, Riho" sort="Sogabe, Riho" uniqKey="Sogabe R" first="Riho" last="Sogabe">Riho Sogabe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/an2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000128 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd -nk 000128 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= an2020
|étape= Analysis
|type= RBID
|clé= PMC:6983437
|texte= Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/an2020/Analysis/RBID.i -Sk "pubmed:32001954" \
| HfdSelect -Kh $EXPLOR_AREA/Data/an2020/Analysis/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |